Abstract
Objectives: The objective of the study is to identify the incidence of drug-related problems coming to the EMD, classify, and identify the risk factor for DRP.
 Methods: This was a prospective observational study conducted in the emergency department for a period of 6 months. The patients admitted through EMD with DRP were identified and then were classified according to Hepler and Strand, 1990 and Classen et al., 1997.
 Results: A total of 109 patients were identified with DRP in our study. Among them, major part was contributed by ADRs (69.7%), non-adherence (27.5%) followed by sub-therapeutic dosage, and untreated indication and overdosage (0.91%). The major organ system involved in DRPs was found to be neurological system (26.60%) and gastrointestinal system (23.85%). The major causative drug class for DRP was found to be anti-thrombotic agents (27%), and the major risk factor for the development of DRP was found to be polypharmacy.
 Conclusion: Drug-related problems are becoming one of the major reasons for the EMD admissions in the hospitals. It can cause significant burden to the society and to the health of the people.
Highlights
IntroductionAny number of outcomes is possible. Most commonly, the patient benefits from the pharmacotherapeutic interventions; there is only a fine line of distinction between the anticipated outcome and side effect of the drug
When people use medication, any number of outcomes is possible
The data were collected to determine the incidence of admissions through the EMD due to drug-related problem (DRP), identify them, and to classify them based on strand et al classification mentioned earlier
Summary
Any number of outcomes is possible. Most commonly, the patient benefits from the pharmacotherapeutic interventions; there is only a fine line of distinction between the anticipated outcome and side effect of the drug. Any deviation from the intended beneficial effect of medication can result in drug-related problem (DRP) [1]. The problems related to drugs represent a major cause of morbidity and are thought to cause between 10% and 30% of all hospital admissions in elderly patients [2]. DRPs pose a challenge to the physician, pharmacist, and other healthcare professional since it alters the expected therapeutic outcome. It increases the health-care costs of the patient. Since the economic impact of DRPs is high, it is important to identify and resolve them. It is important to categorize the DRPs. There are 8 major types of DRPs that have been identified
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