Abstract
Objectives: The current study was undertaken to review and assess the medication usage pattern in patients with chronic kidney disease (CKD). Methods: A 12-month prospective observational study was carried out at Shadan Teaching and General Hospital, Peerancheru (Hyderabad), involving 384 CKD patients considering the inclusion and exclusion criteria. Medication evaluation for optimization was done using the World Health Organization (WHO) core prescribing indicators. Data collected were entered using Microsoft Excel. Descriptive statistics such as mean, percentage, and standard deviation (SD) were used to present sociodemographic characteristics of the study participants. Results: Out of the total of 384 patients, 249 (65%) were male and 135 (35%) were female with a mean age of 58.28 (SD: 13.12). A total of 384 prescriptions were scrutinized with a total of 3634 drugs, out of which drugs acting on the cardiovascular system were the most prescribed drugs (36.37%). The average number of drugs per prescription was found to be 9.08 considering the total number of prescriptions. The percentage of drugs prescribed by generic name was 15.57%. The percentage of encounters with antibiotics was 25%, whereas the percentage of encounters with injections was 86%. The percentage of drugs prescribed from the Essential Drug List or Formulary was found to be 26.36%. Conclusion: Assessment of medication usage patterns using the WHO core indicators in CKD patients helps to reinforce the current hospital guidelines for the optimal usage of medications. The introduction of a clinical pharmacist along with a multidisciplinary team provides intensive care to the patients and helps to improve the clinical outcome.
Highlights
The kidneys are organs that serve a number of essential regulatory roles
Due to the rise in the prevalence and incidence of chronic kidney disease (CKD), there is a major threat among the general population
A total of 384 patients were included in the study considering inclusion and exclusion criteria
Summary
The kidneys are organs that serve a number of essential regulatory roles. Most of us know that our kidneys function as filters, removing metabolic wastes and toxins from the blood and excreting them through the urine. The kidneys help maintain the body’s water balance, electrolyte balance, and acid-base balance. The kidneys produce or activate hormones that are involved in erythrogenesis, calcium metabolism, and the regulation of blood pressure and blood flow [1]. Due to the rise in the prevalence and incidence of chronic kidney disease (CKD), there is a major threat among the general population. It remains a mainstay problem throughout the world. As per the World Health Organization (WHO), the annual death rate of 850,000 contributed by this ailment [2]
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