A Prospective Observational Study on Medication Use Management and Prevalence of Cardiovascular Disease with Comorbidities in a Tertiary Care Hospital

Abstract

Background and Aim Medication use management involves a set of regulations and analytical techniques for defining comprehending and assessing medicine prescription distribution and consumption and also evaluating measures to improve the efficacy of these processes. The present study aimed to assess the medication use pattern prevalence and comorbidity conditions associated with cardiovascular diseases CVD.Methods A prospective observational study was conducted for a duration of six months in the inpatient medicine department of Chigateri District hospital Davangere Tertiary care teaching hospital. Two hundred four case reports of patients with CVD were reviewed and details such as demographics specified drugs prescribed Health Related Quality of Life HRQOL were recorded.Result Two hundred four patients were enrolled out of which 57.35 were males and 42.65 were females. Most of the patients were in the age range of 58-67 years. The most prevalent CVD treated was hypertension HTN 28.23 and the most common comorbidity associated was HTN 32.17. Social habits like smoking 13.75 and HTN 16.92 were found to be the most frequent associated risk factors in CVD patients. The most commonly prescribed class of drugs was antiplatelet 28.41 the common prescribed drug was Furosemide 13.39 and Fixed Dose Combination FDC was Ecosprin gold Atorvastatin Clopidogrel Aspirin 35.29. Most of the prescriptions showed polypharmacy 84.31. While assessing the HRQOL physical component summary PCS 56.94 and mental component summary MCS 54.24 were in a modest range.Conclusion The most prevalent type of CVD was HTN. HTN and DM were the prevalent comorbid conditions among the study population. In the study polypharmacy was noted which may have an impact on rationality. Statins and antiplatelet use was appropriate however excessive use of Furosemide must be controlled. Proper prescription writing increases patient treatment compliance which promotes reason.