A Prospective Observational Study of the Correlation between Hormone Receptor Status and Other Prognostic Factors in Carcinoma Breast in a Rural Set Up in Central India

Abstract

Breast cancer is a major concern in modern India. The growing population of the patients and the increased death toll require immediate attention from the scientific and medical community. Patients’ age, socio-economic condition, and disease awareness play vital roles in the disease onset and progression. In this study, we have conducted a rigorous survey between 2012 and 2014 and investigated all possible contexts in relevance to the disease. From socio-economic to clinical and histopathological relevance were explored. Detail analysis was done for 112 patients. Our data shows Indian scenario having differences not only in stage at presentation with poorer survival but also that the age at presentation is almost a decade earlier than western studies. Only 8% of the participant patients were found to be nulliparous. Very few patients (11.60%) were found to be linked with the disease hereditarily. Statistical co-relation was found between ER status, PR status, lymph nodes, and age of the patients. Our study has shown similarity with the earlier studies as well as dissimilarity in certain facts. We expect this study will increase the present understanding of breast cancer in India.