A prospective observational study of impact of COVID-19 infection on maternal near miss cases in tertiary care centre

Abstract

Introduction: During pregnancy the immune system is altered, which predisposes to respiratory viral infections. COVID’ 19 caused by SARS COV2 is highly infectious disease and has spread rapidly almost around the globe. Since the emergence of SARS-CoV-2 in Wuhan, Hubei Province, China during December 2019, it has caused thousands of morbidities and mortalities around the globe. Materials and Methods: A prospective observational study including all consecutive pregnant women with COVID19 infection. This study was conducted at Department of Obstetrics and Gynecology, Velammal Medical College, Madurai from 1 January 2020 to 20 June 2020. Selection criteria Eligibility criteria included pregnant women with quantitative real-time polymerase chain reaction (PCR) or dual fluorescence PCR-confirmed SARS-CoV-2 infection visiting to the hospital in out-patient department undergoing admission and visiting emergency department. Procedure Data on impact of COVID-19 infection on maternal morbidity and outcomes were extracted and analysed. Results: Of the 76 non-COVID-19 near miss cases, 10 were patients who had disseminated intravascular coagulation as a result of intra uterine fetal death, 20 patients had eclampsia, 10 underwent obstetric hysterectomy, 8 patients had postpartum haemorrhage, 2 was a patient with seizure disorder, 18 patients had LSCS under general anaesthesia, 8 patients had ruptured tubal ectopic pregnancies.