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Abstract
BackgroundDuring growth, the skeletal structures adapt to the increased loading conditions and mature to a fully-grown skeleton. Subchondral bone density reflects the effect of long-term joint loading and it is expected to change over time. The aim of this study was to describe the long-term changes in the density distribution of the subchondral bone of the talus of healthy Labrador Retrievers in a prospective study.ResultsThe subchondral bone density distribution was evaluated using computed tomographic osteoabsorptiometry (CTOAM). Visually, all joints showed very similar density distribution patterns. No significant differences in the topography of the density maxima were found between t1 and t2. The mean density, maximum density, and maximum area ratio (MAR) were significantly increased with increasing age.ConclusionsThe subchondral bone density of the talus of healthy Labrador Retrievers increases with increasing age. It is likely an adaptive response of the subchondral bone due to increased joint loading during growth.
Highlights
During growth, the skeletal structures adapt to the increased loading conditions and mature to a fully-grown skeleton
The goal of this study was to evaluate subchondral bone density, using computed tomographic osteoabsorptiometry (CTOAM), in the talus of healthy Labrador Retrievers at different ages, using a longitudinal study design, in order to document the adaptation of the subchondral bone plate with increasing age
Qualitative interpretation of the subchondral bone density distribution Based on the false colour scale, the overall density increased between t1 and t2 over the entire joint contact area
Summary
The skeletal structures adapt to the increased loading conditions and mature to a fully-grown skeleton. Subchondral bone density reflects the effect of long-term joint loading and it is expected to change over time. Skeletal structures play an important role in vertebrate limb mechanics: apart from allowing locomotion, they have an import role in weight bearing and the associated transfer of forces through joints. The bone strains, induced by loads acting on the bones as a result of weight bearing and muscle action [1, 4] are dedicated mechanical stimuli for bone adaptations. This adaptive process is referred to as mechano-transduction and induces geometrical adaptation of the bone as well as tissue-level adaptations [5,6,7].
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