Abstract

CRMO is a rare, orphan auto-inflammatory disease characterized by recurrent episodes of pain associated with sterile bone inflammation. There is no consensus on the optimal treatment.

Highlights

  • chronic recurrent multifocal osteomyelitis (CRMO) is a rare, orphan auto-inflammatory disease characterized by recurrent episodes of pain associated with sterile bone inflammation

  • Retrospective descriptive case series of nine children diagnosed as CRMO at the Department of Pediatric Rheumatology at Hacettepe University, Ankara, Turkey

  • Acute phase reactants returned to normal, physician and patient/parent visual analogue scales significantly improved in all patients after etanercept treatment

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Summary

Introduction

CRMO is a rare, orphan auto-inflammatory disease characterized by recurrent episodes of pain associated with sterile bone inflammation. A proposed treatment scheme for chronic recurrent multifocal osteomyelitis (CRMO): a case series of nine patients Objectives The aim of this study was to review our CRMO patients and report our results with etanercept treatment in patients with a resistant course in CRMO. Methods Retrospective descriptive case series of nine children diagnosed as CRMO at the Department of Pediatric Rheumatology at Hacettepe University, Ankara, Turkey.

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