Abstract
A detailed procedure for testing linearity of calibration curves in method validation by the ordinary least squares method (OLSM), including experimental design, estimation of the parameters, outlier treatment and evaluation of the assumptions, was proposed. The theoretical background was discussed and the assumptions considered were: (i) normality, homoscedasticity and independency of residuals and (ii) adjustment to the correct model. The procedure involved precise statistical techniques that were easily carried out by any commercial spreadsheet software. The suitability of the procedure for assessing linearity was demonstrated by the application in food analysis.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
