A primary study of endoscopic closure of acute gastric perforation using twin grasper combined with endoloops in a porcine survival model

Abstract

Objective To evaluate the feasibility and efficacy of twin grasper combined with endoloops on closing acute stomach perforation. Methods Two experimental porcines of stomach perforation underwent endoscopic closure by twin grasper combined with endoloops. Survival conditions and closure of perforating were observed. Results Mild infection and abdominal adhesions were observed in one week after operation. The nylon rope fell off and an ulcer-like lesion was presented in the closed position. The methylene blue leak test was negative. Histologic examination revealed chronic inflammatory cells infiltration, granulation, fibroplasias, and regenerative mucous membrane crawling toward the center of perforation. Conclusion The technique of twin grasper combined with nylon ropes in closing the acute stomach perforation is feasible and effective. Key words: Gastric perforation; Animal experimentation; Twin grasper; Endoloop