Abstract
The lack of a primary method for determination of optical parameters remains a significant barrier in optical study of turbid media. We present a complete system of experimental setups and Monte Carlo modeling tools for fast and accurate solution of the inverse problem from the measured signals of homogeneous turbid samples. The calibration of the instrument and validation of the Monte Carlo modeling have been carried out to ensure the accuracy of the inverse solution. We applied this method to determine the optical parameters of turbid media of 10% intralipid between 550 and 940 nm and 20% intralipid between 550 and 1630 nm.
Highlights
Development of a primary method as the “gold standard” for determination of macroscopic optical parameters of turbid media is highly desired in the optical study of turbid media such as biological tissues
A reasonable one appears to be given by the Fresnel formulae for plane electromagnetic waves [2] in which light transportation at an interface depends on the mismatch of the refractive index between the two neighboring media
We present a system of experimental setups and Monte Carlo modeling tools that have been developed over the last few years in our laboratory to obtain the full set of parameters
Summary
Development of a primary method as the “gold standard” for determination of macroscopic optical parameters of turbid media is highly desired in the optical study of turbid media such as biological tissues. Optical parameters may be defined precisely on the basis of a local theory with the radiative transfer equation (RTE) that has been widely used for modeling light transportation in turbid media [1]. A reasonable one appears to be given by the Fresnel formulae for plane electromagnetic waves [2] in which light transportation at an interface depends on the mismatch of the refractive index between the two neighboring media. Even though no analytical model exists for complex turbid media such as the human skin tissues, experimental data on coherence reflectance curves demonstrate a good agreement with the Fresnel formulae [3]. It became customary to use μa, μs, p(s, s’) and the real refractive index nr for optical characterization of a turbid medium.
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