Abstract
Background: Acinetobacter species has emerged as an important pathogen globally in various infections especially in hospital acquired infections. Objectives: This study was conducted to determine the prevalence, and antibiotic resistance pattern of Acinetobacter species from various clinical samples. Materials and Methods: The study included a total of 1000 clinical samples, collected from patients treated in P.D.U. Hospital Rajkot-a tertiary care hospital in Gujarat, India were included in study period from November 2012 to August 2014. Isolation , Identification and sensitivity of Acinetobacter species were performed by manual method. Results: 48 (4.8%) patients clinical samples showed growth of Acinetobacter species. Acinetobacter species isolation rate from blood were 24(50%), pus 15(31.25%), urine 4(8.33%), CSF 2(4.18%), sputum 1(2.08%), plural fluid 1(2.08%) and tracheal aspirate 1(2.08%). Resistance observed to Meropenem was 41.67%, Piperacillin -Tazobactum 58.34%, Amikacin 52.09%, Ceftazidime 79.71%, Gentamicin 62.5% and Levoflaxacin 68.75%. This data suggest that Acinetobacter isolated from hospital exhibits resistanas to multiple antimicrobial drugs. Conclusion: The study will help to implement better infection control strategies and improve the knowledge of antibiotic resistance patterns of Acinetobacter species in our region.
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