Abstract
Objective To evaluate the feasibility and value of automated cardiac motion quantitation (aCMQ) for measuring the global and regional longitudinal strain of left ventricle in fetuses. Methods One hundred and eighteen normal fetuses were divided into 4 groups by gestational age, standard four-chamber view clips were collected, the global and segmental longitudinal peak systolic strain of the left ventricle were measured by aCMQ, the variabilities of interobserver and intraobserver were analyzed. Results The success rate of aCMQ analysis was 89%. There was no significant correlation between the gestational age and the global and segmental longitudinal peak strain of the left ventricle (r were 0.00-0.14, all P 0.05). The strain of the apex segment was higher than those of the base and middle segment (P<0.05). Interobserver and intraobserver variability showed a small bias among the observers. Conclusions aCMQ is a feasible and reproducible approach to quantitatively evaluate normal cardiac function of fetus and may have potential in fetuses with congenital heart diseases. Key words: Echocardiography; Fetus; Ventricular function, left; Automated cardiac motion quantitation
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