A Preliminary Assessment of Cerebral Surface Strain

Abstract

Background: Craniotomies are commonly performed neurosurgical procedures. Quantitating cerebral surface strain may facilitate the identification of intracerebral pathology and improve intraoperative management of underperfused brain tissue. Objective: The aim of this study was to test the use of digital image correlation software to quantify cerebral surface strain of intraoperative cerebral tissue during craniotomies. Methods: Ncorr, an open-source software program, was used to perform digital image correlation analysis from publicly available craniotomy videos. Mann-Whitney U tests were then utilized to assess statistical differences between craniotomy datasets. Results: Four different craniotomies were retrospectively examined, and the acquired cerebral surface strain data were subsequently extracted and analyzed. Statistically significant cerebral surface strain values were identified when comparing the four craniotomies. Additional prospective research is needed to establish baseline ranges of cerebral surface strain and to further understand the potential utility and limitations of this non-invasive intraoperative monitoring technique. Conclusion: This preliminary study successfully demonstrated the use of computer-based image analysis for the non-invasive quantification of cerebral surface strain during neurosurgery.