Abstract

A Predictive Model for Pregnancy Development In Thoroughbred Mares with Placental Insufficiency and Its Correction

Highlights

  • The equine placenta is a main component of gestation

  • The events of biochemical activity of equine placenta have been described by Wooding & Flint (1994).Allen & Stewart (2001) whose laboratory has perhaps contributed the most information to our understanding of this interesting organ

  • According to the results of the clinical examination during pregnancy, placental insufficiency with such characteristic symptoms as edema, hypertension and proteinuria was diagnosed in 26.4% of cases; premature parturition, which occurred due to excessive training of the pregnant mares – in 16.6% of cases; abortions of mainly traumatic nature – in 2.5% of cases; kidney disease as a consequence of nephropathy – in 35.5%; anemia as a result of vitamin deficiency and microelementosis – in 19.0% of mares

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Summary

Introduction

The equine placenta is a main component of gestation. The histological background to the study of the equine placenta has been summarized by Steven (1975) and Steven & Morris (1975). The events of biochemical activity of equine placenta have been described by Wooding & Flint (1994).Allen & Stewart (2001) whose laboratory has perhaps contributed the most information to our understanding of this interesting organ. The equine placenta allows the transfer of nutrients and oxygen from the dam’s blood to the fetus and a diffusion of waste products from the fetus to the dam’s blood. This is the only one way to get the necessary sources for foal, including immunoglobulins. The placenta synthesizes steroids, peptides, glycoproteins and other biological active molecules, and inactivates other hormones such as catecholamines, glucocorticoids, thyroxine and prostaglandins (Carol, Allen, Steven 1976)

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