A Predictive Geological Tool of Type 3 Diabetes (Alzheimer’s Disease): The Polygonal Vortex Mineralisation Model a Medical Geology Perspective

Abstract

Essential selenium and zinc deficiencies biochemistry and physiology is reviewed to impact neurobiology and Alzheimer’s significantly whilst metal pollutants impact early Alzheimer’s progression. A predictive bio-geospatial tool for such impacts considers Taranjebin-Mannagum selenium, by way of the Polygonal Vortex Mineralization Model (PVM) in the central Asian Metallogene. Manna becomes Taranjebin on selenium hyper-accumulation, then highly valued ethnomedically for immune disorders, hyperbilirubinemia, also mitigating diabetes, including Alzheimer’s risk, combating low birth weight known to influence diabetes. Diabetes mitigation source regions of hyper accumulating organic selenium are described within deficient desert terrains. PVM was initially developed as a predictive mineral exploration tool. It is proposed for the first time a novel use as a geological framework of potential public health risks including diabetes. PVM is now intended to cover all forms of mineralization and anthropogenic by products. Similarly, to mineral exploration targeting, PVM can help ‘prospect’ for health risks. That’s helpful, as most communities never undergo geogenic epidemiological studies. PVM defines mineralization fluid pathways, often in polygonal fracture sets, from microscopic to macro fractal niche scaled, as previously reported, providing high fracture surface activity. Essential minerals and or pollutants are then geologically remobilization to biota, impacting health through food bowl, water and air quality. Significantly, PVM-geogenic models may provide mappable ‘Medical Geology indicators’ of essential elements or pollution when qualified biogeochemically, as “Geogenic Public Health Indices” (PVM-HI). Ideally, they and other indices help produce “The Medical Geology Map of The Globe”, supporting public health in developing countries and where epidemiological and Metallogene supervision of it is sparse. One should add warfare and industrial metalliferous debris ‘indices’. The author’s expectation is this paper will engender PVM-HI debate on such “prospecting” utilities for unrecognized Alzheimer’s, other health risks, and help unravel their core pathways through bio-geospatial analysis. Taranjebin selenium biogeochemical-ethnomedical qualified data varying with geology provide PVM-HI examples. Selenium-bio-fertility is herein linked to plate subduction beneath former Iran-Pakistan-Afghanistan micro plate collision boundaries. Interestingly, present country borders conform to former micro plate boundaries, though cultural aspects follow geological features. This has physiographic-geogenic mobility implications for selenium and community Medical Geology. Selenium, sourced primarily from evolving calc-alkaline to alkalic Cenozoic magmatism and fault fracture networks (PVM), confers Taranjebin ethnomedical quality, transitioning higher towards back arc environments respectively. The Cimmerian orogenesis responsible effected the Eurasian plate between Turkey and Thailand since the Mesozoic, widening PVM-HI Medical Geology ‘prospecting’ scope. Gondwana micro continent collation included the Central East Iran Microplate (CEIM), where the Fabaceae manna gum hosts, and Alhagi maurorum was studied. Taranjebin selenoglycoproteins are considered the active selenium species utilized by primal desert communities. Taranjebin with other manna gums are still widely traded, as they were in antiquity. With demographic changes underway it is essential primal confounding physicochemical environment factors and metal speciation impacting Alzheimer’s are studied soon, with epidemiology, genetics and anthropology. Mediterranean to Central Asia manna selenium studies are recommended before modern life completely overshadow primal geogenic factors in diabetes. This Medical Geology perspective will help unravel some confounding factors in type 3 diabetes (Alzheimer’s disease).