Abstract
A straightforward synthesis of a cyclosporine−fluorescein conjugate through the MeBmt hydroxyl group was developed. Reaction of cyclosporine A in phosgene/toluene solution with added triethylamine, followed by subsequent reaction with 4‘-aminomethylfluorescein, produces good yields of the cyclosporine−fluorescein conjugate.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have