Abstract

Research on giant vesicles is becoming increasingly popular. Giant vesicles provide modelbiomembrane systems for systematic measurements of mechanical and rheologicalproperties of bilayers as a function of membrane composition and temperature, as well ashydrodynamic interactions. Membrane response to external factors (for exampleelectric fields, ions and amphiphilic molecules) can be directly visualized under themicroscope. In this paper we review our current understanding of lipid bilayers asobtained from studies on giant unilamellar vesicles. Because research on giantvesicles increasingly attracts the interest of scientists from various backgrounds, wealso try to provide a concise introduction for newcomers in the field. Finally, wesummarize some recent developments on curvature effects induced by polymers,domain formation in membranes and shape transitions induced by electric fields.

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