Abstract
Objective To describe a potential new use of gonadotropin-releasing hormone (GnRH) antagonists. Design Case report. Setting Assisted conception unit at a teaching hospital in the United Kingdom. Patient(s) A 37-year-old woman undergoing in vitro fertilization (IVF) who accidentally stopped using GnRH agonists after starting ovarian stimulation. Intervention(s) A GnRH antagonist was used to avoid a luteinizing hormone (LH) surge and hence “rescue” the cycle. Result(s) Successful oocyte retrieval was carried out, two embryos transferred, and a viable twin pregnancy ensued. Conclusion(s) This may be a new indication for the use of GnRH antagonists.
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