Abstract
To rapidly achieve teicoplanin trough (Cmin) concentrations ≥20 mg/l suggested for sternal sepsis, loading doses higher than 6 mg/kg 12-hourly might be warranted [1].
Highlights
Sepsis is primarily a disease of the aged and 60% of sepsis occurs in patients older than 65 years, 80% of deaths due to sepsis occur in this age group
The purpose of the study is to elucidate the immunological changes that occur in Klotho mice after sepsis in order to identify therapeutic targets for sepsis that occurs in aged individuals
The 25(OH)D deficiency remains a significant predictor of acute kidney injury following multivariable adjustment
Summary
Sepsis is primarily a disease of the aged and 60% of sepsis occurs in patients older than 65 years, 80% of deaths due to sepsis occur in this age group. The aim was to evaluate the association between admission levels of CFD and severe sepsis outcome in patients hospitalized in intensive care utilizing the new assay. Implementation of a ventilator-associated pneumonia (VAP) bundle as a performance improvement project in the critical care units for all mechanically ventilated patients aiming to decrease the VAP rates over the study period at four major teaching hospitals in Damascus. The combination of high positive end-expiratory pressure (PEEP) and low tidal volume (VT) decreases some risks of mechanical ventilation, including pulmonary overdistention, damage due to cyclic opening and closing of the alveoli, and inflammatory responses that can lead to multiple-organ dysfunction. The timing and location for optimal post-ICU rehabilitation programs remain to be established
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