Abstract

A serial analyzer with polarographic and spectrophotometric detection has been designed to speed up content uniformity tests in pharmaceutical quality control laboratories. The advantages of flow and discrete analysis are combined to provide the required speed and precision. Pharmaceutical preparations of diazepam, nitrazepam, spironolactone and pyridinolcarbamate have been tested satisfactorily. The system is easily constructed from commercially available hardware and a few home-made units. The problem of sample deaeration before polarographic measurements in flow systems is solved succesfully in a very simple way.

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