A Placebo-Controlled Trial of a HEPA Air Cleaner in the Treatmentof Cat Allergy

Abstract

1. Wood RA, 2. Johnson EF, 3. Van Natta ML, 4. Hua Chen P, Eggleston PA (1998) Am J Respir Crit Care Med. 158:115–120. [OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] #### Purpose of the Study Air cleaners and air filtration devices have enjoyed considerable popularity as a form of environmental control to remedy allergic problems. There are, however, many unanswered questions in regard to their efficacy. This study attempts to address the question of efficacy of the high-efficiency particulate arrestor (HEPA) cleaners in reducing allergen levels and disease activity in the homes of cat-allergic patients who continue to live with the triggering allergen (cat). ##### Study Population This study involved adults who had asthma and/or allergic rhinitis. They all had a history of allergic symptoms with cat exposure to the extent they required daily medications. They also had at least one cat in the home. ##### Methods A 1-month baseline period helped to determine the minimum amount of medication needed to control asthma and/or allergic rhinitis symptoms. Daily … [1]: {openurl}?query=rft.jtitle%253DAmerican%2BJournal%2Bof%2BRespiratory%2Band%2BCritical%2BCare%2BMedicine%26rft.stitle%253DAm.%2BJ.%2BRespir.%2BCrit.%2BCare%2BMed.%26rft.issn%253D1073-449X%26rft.aulast%253DWOOD%26rft.auinit1%253DR.%25A0A.%26rft.volume%253D158%26rft.issue%253D1%26rft.spage%253D115%26rft.epage%253D120%26rft.atitle%253DA%2BPlacebo-controlled%2BTrial%2Bof%2Ba%2BHEPA%2BAir%2BCleaner%2Bin%2Bthe%2BTreatment%2Bof%2BCat%2BAllergy%26rft_id%253Dinfo%253Adoi%252F10.1164%252Fajrccm.158.1.9712110%26rft_id%253Dinfo%253Apmid%252F9655716%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.1164/ajrccm.158.1.9712110&link_type=DOI [3]: /lookup/external-ref?access_num=9655716&link_type=MED&atom=%2Fpediatrics%2F104%2FSupplement_2%2F380.3.atom [4]: /lookup/external-ref?access_num=000074730700019&link_type=ISI