A Pincer Cobalt Complex as Catalyst with Dual Hydrogenation Activities for Hydrodeoxygenation of Ketones with H2†

Abstract

Comprehensive SummaryReductive deoxygenation of ketones using H2 is a highly desirable but also challenging transformation in both chemical synthesis, industrial‐scale petroleum and biomass feedstock reforming processes. Herein, we report a cooperative cobalt/Lewis acid (LA)‐catalyzed hydrodeoxygenation of ketones using H2 as the reductant. In particular, the newly developed pincer cobalt catalyst possesses dual hydrogenation activities for both ketones and alkenes under the same reaction conditions. This reaction features a broad substrate scope, excellent functional‐group compatibility, and potential applicability.