A pilot study to evaluate the safety and efficacy of ‘Canna Relief’ Stress Management Oil after oral consumption in patients with Stress and Mild to Moderate Anxiety Disorder

Abstract

Background: Clinical manifestation of Anxiety is included in as a Mansik vyadhi in Ayurveda. Anxiety disorders are the world’s most common mental disorder affecting 4.05% of global population, translating to 301 million people. The prevalence of anxiety disorders has been rising over the last three decades. Due to the wide spectrum of diseases, much prevalence in society, and lack of effective medicines, the disease has been chosen for the trial. Aim: The aim of this study was to study the efficacy of CannaRelief stress management oil in the management of Anxiety. Materials and Methods: 40 clinically diagnosed patients were selected and administered CannaRelief stress management oil – 4 drops sublingual in night after food for 60 days. Study Design: It was a single‑center, single arm, open‑label, phase 4, pilot study. Results: The drug showed statistically significant results in terms of subjective parameters. It was found that after taking medicine sleep quality was increased in maximum no. of patients. 50% patient showed reduced level of salivary cortisol level and 60% patient showed reduced level of salivary amylase. salivary amylase showed significant result after treatment. Conclusion: CannaRelief stress management oil is effective in the management of Anxiety disorder.