Abstract

Purpose: Chronic migraines and headaches are significant public health problems, and their symptomatologies have been positively linked to diet. We explored if individuals suffering from chronic migraines/ headaches who required medication treatment had improvement in symptomatology and subjective ratings of QoL when following an immune-reactive food exclusion diet based on the results of the ImmunoBloodprint test, an IgG-mediated food sensitivity assay. Methods: Thirty-seven subjects, aged 18 and over, took part in the study. Subjects had to eliminate all reactive foods from their diet for 90 days. Migraine intensity and frequency were measured using the MTAQ, and QoL was assessed with the SF-36 survey at base- line and 30-, 60-, and 90-day follow-up. Results: Sub- jects who eliminated IgG-mediated reactive foods from their diet had reductions in migraine symptomatology and had improvements in nearly all indicators of QoL, according to the SF-36, from baseline to 90-day follow-up. Conclusions: Subjects were able to improve their migraine symptoms and QoL in response to eliminating IgG reactive foods from the diet. This test may represent a strategy to help mediate chronic migraine symptomatology without the use of medication.

Highlights

  • Headaches and migraines affect 46% of the global adult population, and they constitute a significant public health issue given their negative effect on quality of life (QoL) and resulting level of disability [1,2]

  • We explored if individuals suffering from chronic migraines/ headaches who required medication treatment had improvement in symptomatology and subjective ratings of QoL when following an immune-reactive food exclusion diet based on the results of the ImmunoBloodprint test, an IgG-mediated food sensitivity assay

  • Pairwise comparisons revealed that the Migraine Therapy Assessment Questionnaire (MTAQ) total score at baseline was marginally higher than at 30 days, at 60 days, and at 90 days

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Summary

Introduction

Headaches and migraines affect 46% of the global adult population, and they constitute a significant public health issue given their negative effect on quality of life (QoL) and resulting level of disability [1,2]. Migraines/headaches are multifactorial and involve several different predispositions, the influences of which vary for each individual person. Many studies positively link diet to symptomatology. Studies have indicated that the percent of patients reporting food as a trigger for migraines range from 12% - 60% with many of them reporting more than one food [3,4,5]. One study evaluated triggers of migraine without aura in 100 subjects and found that in 20 patients migraines were occasionally triggered by foods like chocolate, cheese, wine, tomatoes, nuts, carbonated beverages, and leavened products [6]. An individualized diet to relieve migraine is desirable

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