Abstract
In continuation of our work on Egyptian plants of the genus Zygophyllum, Zygophyllum simplex L. was chosen for the study. Z. simplex L. is one of the common species of the genus Zygophyllum growing in Egypt [1]. The plant growing in North Africa and Arabian region was reported to be used in the treatment of horny patches on the skin [2]. The current phytochemical study of the aerial parts of the plant has resulted in isolation and structural elucidation of seventeen compounds belonging to different chemical classes. The isolated compounds were identified as isorhamnetin (1), isorhamnetin-3-O-glucoside (2), isorhamnetin-3, 7-diglucoside (3), isorhamnetin-3-O-(6'-malonyl)glucoside (4), quercetin-3-O-glucoside (5), quercetin-3-O-(6''-malonyl) glucoside (6), vanillic acid(7), ferulic acid (8), p-hydroxy benzoic acid (9), p-hydroxy acetophenone (10), p-hydroxy acetophenone glucoside (11), androsin (12), adenine (13), thymidine (14), adenosine (15), stigmast-3,6-dione (16), and β-sitosterol-3-O-β-D-glucoside (17). Among the isolated compounds (3, 4, 6, 7-14) are reported for the first time from genus Zygophyllum.
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