Abstract
The photolytic transformation of 2-(2-(2,6-dichlorophenylamino)phenyl)acetic acid (diclofenac) and its transformation products (TPs) (8-chloro-9H-carbazol-1-yl) acetic acid (Cz1), 2-(2-chloro-phenylamino)-benzaldehyde (Ald) and (1,4-dioxo-4,9-dihydro-1H-carbazol-8-yl) acetic acid (Cz4) in aqueous solutions have been studied. The previously unreported TP (Cz4) was isolated by LC and completely characterized by NMR and MS. UV-absorption spectra of diclofenac and three of its TPs were determined and used to calculate disappearance quantum yields. The dominating transformation pathway of diclofenac occurs via initial formation of Cz1 and proceeds to form mainly (Cz4) over 200 min of UV-irradiation. A second minor transformation pathway, which yields Ald as the sole product, was observed only under deaerated conditions.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.