Abstract

Phosphorus-containing amidine 7 was prepared through several steps from L-valine 1. The new ligand for asymmetric reactions was evaluated in the palladium-catalyzed allylic alkylation of 1,3-diphenylprop-2-enyl acetate and pivalate 8a,b with the nucleophile derived from dimethyl malonate as a preliminary study. Excellent levels of asymmetric induction up to 95% e.e. were achieved along with an efficient conversion.

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