A phase 2 study of azacitidine (5-AZA) with or without birinapant in subjects with higher risk myelodysplastic syndrome (MDS) or chronic myelomonocytic leukemia (CMML).

Abstract

7060Background: Inhibitor of Apoptosis Proteins (IAPs) are a family of molecules that are dysregulated in myeloid stem cell disorders and prevent programmed cell death. SMAC (second mitochondrial a...