A pharmacological investigation for therapeutic potential of Callistemon citrinus as an anthelmintic agent (Bottle-Brush Plant)

Abstract

The growing resistance of parasitic helminths to standard anthelmintic medications has sparked increased interest in exploring alternative treatments, particularly those derived from herbal sources. This research focuses on the anthelmintic properties of selected herbal plants, assessing their ability to inhibit and eliminate parasitic worms. Standard extraction techniques were employed to prepare various plant extracts, which were then tested using both in vitro and in vivo assays to determine their effectiveness. The findings revealed that several plant extracts showed significant anthelmintic effects, comparable to those of conventional medications. Phytochemical analysis identified a high concentration of alkaloids, tannins, saponins, and flavonoids, which are thought to be the primary contributors to the observed activity. These results indicate that these herbal plants may serve as promising natural anthelmintic agents, providing a sustainable and environmentally friendly alternative to synthetic drugs. Further research is necessary to isolate and identify the specific bioactive compounds, clarify their mechanisms of action, and assess their safety and efficacy in clinical applications. This study highlights the potential of herbal medicine in developing novel anthelmintic treatments and encourages the integration of traditional knowledge with modern scientific research.