Abstract
The idea of precision medication is turning out progressively to be famous. The utilization of enormous information, genomics and other omics like metabolomics; proteomics and transcriptomics; could soon cause the fantasy of personalized medication to turn into a reality. The most recent advancements in precision medication permit the adjustment of helpful approaches in various pathologies based on the particular molecular interpretation of the patient. Precision medication (PM) represents a new way of thinking about infection detection; prevention and treatment. The use of PM grounds in an emerging COVID virulent disease is becoming more prominent. Various discoveries revealed that severe acute respiratory disorder COVID-2 (SARS CoV-2) is accountable for the Coronavirus disease -2019 (COVID-19), which caused slew of procedures to restrict viral spread, affecting people's habits and lifestyles. According to the viral genomic sequencing, the SARS-CoV-2 spike protein uses angiotensin-converting enzyme 2 (ACE2), which is established on the ciliated epithelial cells of the human lungs as its particular receptor. In this specific situation; precision medication is an integrative helpful methodology that thinks about conventional elements (i.e. age, sex, clinical aggregate), just as arising hereditary qualities and connections with natural components, to individualize prevention; diagnosis, treatments and prognosis. The aim of this review was to summarize how precision medicine is impactful in the management of COVID-19.
Highlights
Coronaviruses (CoVs) have emerged as one of the most common microorganisms in the recent outbreaks of respiratory sickness; indicating a serious global health issue (de Wit et al, 2016)
Severe acute respiratory syndrome (SARS) outbreaks were caused by two species, one in China in 2002-2003 by Severe acute respiratory syndrome coronavirus (SARS CoV), and the other by the Middle east respiratory syndrome coronavirus (MERS CoV); both of which emerged in 2012 and demonstrated limited human-to-human transmission but a high case fatality rate (CFR), as highlighted by de Wit et al, (2016)
Huang et al, (2020) found that the severity of COVID-19 illness was connected to the increased D-dimer levels
Summary
Coronaviruses (CoVs) have emerged as one of the most common microorganisms in the recent outbreaks of respiratory sickness; indicating a serious global health issue (de Wit et al, 2016). SARS-CoV-2; is a coronavirus that causes severe acute respiratory symptoms; emerged in China around the end of 2019 and spread quickly over the world, producing the Coronavirus disease 2019 (COVID-19) epidemic (Crisci et al, 2020). In light of information on the pathophysiological components and varieties of clinical aggregates of a disease, PM seeks to categorize the finest administration techniques that allow for a precise conclusion. This encourages a preventative, proactive and restorative methodology tailored to the patient's characteristics and needs; advancing the patient's health (Andryukov et al, 2021). One of the components had been identified as the loss of smell and taste
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