Abstract
THE production of antibiotic substances by several species of Aspergillus has been reported, and several have been purified or isolated1–5. Wilkins and Harris6 described the production of a substance, active against staphylococci, by Aspergillus giganteus. A culture of the mould (kindly supplied by Dr. Wilkins) was grown on a medium consisting of malt extract, 2 per cent, peptone, 1 per cent, M triethanolamine buffer pH 8.2, 5 per cent. The antibiotic has been purified and a crystalline degradation product prepared. In all its chemical and biological properties it appears to be very similar to penicillin7.
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