Abstract
The Journal of the Postgraduate Institute of Medicine (JPGIM) is an open access, peer-reviewed, biannual journal published by the Postgraduate Institute of Medicine (PGIM) of the University of Colombo (UOC), Sri Lanka. The JPGIM aims to publish articles relevant to clinicians, policymakers, and researchers on topics relating to the practice of medicine, medical education, professionalism, integrity, and ethics of the research enterprise. The JPGIM has been in publication since 2014 and publishes accepted manuscripts online immediately after copy-editing, enabling rapid dissemination of scientific knowledge. The published articles are compiled into two issues in June and December.The Journal practices a double-blind peer review policy. The JPIGM does not charge any article processing or publication fee.We recommend that you review the About the Journal page for the journal's section policies, as well as the Submission Guidelines. Authors need to register with the journal prior to submitting or, if already registered, can simply log in and begin the five-step process.
Highlights
Adult-onset Stills disease (AOSD) is an autoimmune inflammatory disorder of unknown aetiology, characterized by quotidian fever, arthritis and an evanescent rash [1]
The clinical course of AOSD can be categorized into two main patterns: systemic pattern and chronic articular pattern
Patients with the chronic articular pattern have persistently active disease in which articular symptoms predominate, and this usually leads to destructive arthritis [2,3,4]
Summary
Adult-onset Stills disease (AOSD) is an autoimmune inflammatory disorder of unknown aetiology, characterized by quotidian fever (fever occurring daily), arthritis and an evanescent rash [1]. Erythrocyte sedimentation rate, C-reactive protein, lactate dehydrogenase and serum ferritin were 98 mm/1st hour, 347.6 mg/L, 525 U/L and 13967 ng/ml respectively Her chest Xray showed bilateral nodular shadows with a predilection for the lower zones and complete liver and renal function tests, urine analysis and coagulation profile were normal. An alternative diagnosis adult-onset Still’s disease was made and she was started on methyl prednisolone pulse 500 mg IV daily for 3 consecutive days followed by high dose prednisolone 60 mg oral daily Her symptoms and signs dramatically improved following initiation of steroid therapy and she was discharged from the ward and is being followed up at the rheumatology and respiratory clinics
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