Abstract
Current preparation methods for hydrogels based on redox or photopolymerization of water soluble monomers are simple to use, and flexible, but have the drawback of requiring additional modification steps for tuning or introducing properties for specific purposes. We have devised a simple and rapid synthetic strategy to prepare hydrogels possessing reactive sites to incorporate any molecules of interest by "Click Chemistry". The strategy is based on the use of propargyl acrylamide (PAm) as comonomer together with acrylamide (AAm) and N,N'-methylene bisacrylamide (BAAm) as crosslinker in photoinitiated polymerization. With the selective reactivity of photochemically generated free radicals towards acrylic function of PAm, hydrogels with clickable acetylene groups can be prepared in one pot, one step manner. Based on the acetylene functionality, any molecule possessing azide groups can be conjugated onto hydrogel by "Click Chemistry" as demonstrated on the example of fluoroscent azide functional pyrene.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
