A numerical model on pulsatile flow of magnetic nanoparticles as drug carrier suspended in Herschel–Bulkley fluid through an arterial stenosis under external magnetic field and body force

Abstract

ABSTRACTA theoretical model for blood flow through an artery with stenosis carrying magnetic particles in the presence of magnetic field and periodic body acceleration is analysed. In the present study, blood is assumed to be Herschel–Bulkley fluid carrying iron oxide nanoparticles. The governing equations are highly non-linear and were solved numerically. The effects of model parameters are investigated and the results are represented graphically. The shear stress at the arterial wall and resistive impedance increases with enhancing values of stenotic height, yield stress, flow behaviour index, consistency index, pulsatile Reynolds number, amplitude of body acceleration, particle concentration and particle mass parameters. In order to treat the circulation disorders, control of the parameters involved in blood flow is necessary. The present model is useful in normalizing the parameter values and hence it can be applied in the field of medicine. The study has significant applications in drug delivery for treating cancer.