Abstract
ABSTRACT It is of interest to research hyperthermia combined with radiation and cytotoxic drugs to enhance the killing of tumors. The crucial problem is to keep surrounding normal tissue below a temperature that will produce harm when heating the tumor tissue. In this study, we develop a numerical model for optimizing laser power in the irradiation of a 3-D triple-layered cylindrical skin structure. The method determines the required laser intensity in order to obtain prespecified temperatures at given locations on the skin surface after a prespecified laser exposure time.
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