Abstract
In this paper, a Kretschmann configuration based surface plasmon resonance (SPR) sensor is numerically designed using graphene-MoS2 hybrid structure TiO2-SiO2 nano particles for formalin detection. In this design, the observations of SPR angle versus minimum reflectance and SPR frequency (FSPR) versus maximum transmittance (Tmax) are considered. The chitosan is used as probe legend to perform reaction with the formalin (40% formaldehyde) which acts as target legend. In this paper, both graphene and MoS2 are used as biomolecular acknowledgment element (BAE) and TiO2 as well as SiO2 bilayers is used to improve the sensitivity of the sensor. The numerical results show that the variation of FSPR and SPR angles for inappropriate sensing of formalin is quite insignificant which confirms the absence of formalin. On the other hand, these variations for appropriate sensing are considerably significant that confirm the presence of formalin. At the end of this article, the variation of sensitivity of the proposed biosensor is measured in corresponding to the increment of a refractive index with a refractive index step 0.01 refractive index unit (RIU). In inclusion of TiO2-SiO2 bilayers with graphene-MoS2, a maximum sensitivity of 85.375% is numerically calculated.
Highlights
Formalin is an ecologically extensively chemical compound that causes cancer to humans [1].Exposure to formalin will possibly cause antagonistic health effects
Refractive index based surface plasmon resonance (SPR) bio-sensing has been widely researched because this sensor technology has a great potential for detection and analysis of chemical and biochemical substances in many important areas including medicine, biotechnology, monitoring of drug, food quality, environment safety, formalin detection, medical diagnosis, enzyme detection, and doxyribonucleic acid (DNA-DNA) hybridization [8,9,10,11,12,13,14,15,16,17,18,19]
At the end of this article, a study of the variation of sensitivity of the proposed biosensor is measured in corresponding to the increment of a refractive index with a refractive index step 0.01 refractive index unit (RIU)
Summary
Formalin is an ecologically extensively chemical compound that causes cancer to humans [1]. Refractive index based surface plasmon resonance (SPR) bio-sensing has been widely researched because this sensor technology has a great potential for detection and analysis of chemical and biochemical substances in many important areas including medicine, biotechnology, monitoring of drug, food quality, environment safety, formalin detection, medical diagnosis, enzyme detection, and doxyribonucleic acid (DNA-DNA) hybridization [8,9,10,11,12,13,14,15,16,17,18,19]. Numerical Kretschmann configuration based refractive index sensor utilizing graphene-MoS2 hybrid layers with TiO2-SiO2 nano particles is designed and investigated, which can explore a new window for the detection of formalin. At the end of this article, a study of the variation of sensitivity of the proposed biosensor is measured in corresponding to the increment of a refractive index with a refractive index step 0.01 refractive index unit (RIU)
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