Abstract
Heparin is widely used to anticoagulation treatment in clinic, while the overdoses of heparin can cause potentially catastrophic complications. Thus, the selective and sensitive detection of heparin is of great importance. Herein, a novel water-soluble AIE-based fluorescent probe (TIBI) with red emission (650nm) has been rationally developed to detect heparin by the electrostatic-interaction and ion replacing strategy. TIBI exhibited excellent selectivity and low detection limit (0.08μM) for detection of heparin. Moreover, TIBI was successfully applied to detect heparin in complicated serum samples with satisfactory results. This study holds great promise for real time monitoring heparin in clinical application.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
