Abstract
Berberine chloride was synthesized starting from pyrocatechol in overall 13.6% yield. The key steps include a Hofmann rearrangement, chloromethylation, nucleophilic substitution, hydrolysis, decarboxylation, and cyclization. All of intermediates were determined by H NMR, C NMR, MS techniques.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have