Abstract
In this paper, we present a waveguide-surface plasmon resonance biosensor. A 450nm period sub-wavelength metallic gratings (SWMGs) were fabricated by nanoimprint, which was then applied to detect the protein layer capping on the grating. Both our measurement and simulation results indicate that the resonance does exist for 450nm pitched gratings. A resonance shift in surface plasmon resonance (SPR) curves of protein films with different refractive indices were investigated, which would be promisingly applied in protein, DNA or drug test. Moreover, a novel angle of incidence (AOI) based detection method was developed to help reduce the cost of the expensive detecting devices.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.