Abstract

Biodegradable zinc alloy stents offer a prospective solution to mitigate incompatibility between artery and permanent stents. However, biodegradable stents are restricted in clinical therapy mainly because of their insufficient support for opening of stenotic vessel. As an effort to resolve this challenging problem, a novel structure of zinc alloy stent which significantly enhanced scaffold performance is proposed in this paper. Subsequently, the functionality of the new stent on reshaping vessels with 40% of stenosis was investigated in contrast with a common stent via finite element analysis. The simulation results show that radial recoiling ratio and dog-boning ratio of the new stent are decreased by 43.2% and 16.3%, respectively, compared with those of the common stent. A larger and flatter lumen is found in the plaque-vessel system deployed with the new stent. It suggests that the geometry of stent has strong influence on its mechanical performance. With strong scaffold capability and brilliant effect on reshaping stenotic vessel, the biodegradable zinc alloy stent-based novel structure is highly promised to be an alternative choice in interventional surgeries.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.