Abstract
AbstractIn this study, we have successfully synthesized a novel probe HL by condensation reaction of acetophenone with 8‐hydroxyquinoline‐2‐carbaldehyde derivative and its structure was characterized by 1H NMR, 13C NMR, IR and HRMS. The probe HL displayed highly selective and sensitive fluorescence “turn on” response as well as naked‐eye color change towards Al3+ in the presence of other competing cations in DMF‐HEPES (5:1, v/v, 10 mM, pH=7.2). The binding mechanisms have been explored though Job's plot, HRMS, 1H NMR and theoretical calculations, which was ascribed to photoinduced electron transfer process (PET) and chelation‐enhanced fluorescence mechanism (CHEF). The ensemble HL‐Al3+ displayed high selectivity to PPi (P2O74−, pyrophosphate) through pulling out Al3+ and releasing free probe HL in physiological conditions. The sensing process was reversible. Furthermore, the cells imaging experiences showed that probe HL could be use as relay on detection of Al3+ and PPi in living PC12 cells.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
