Abstract
A ratiometric fluorescent probe for the detection of Ho3+ in DMSO-aqueous medium was designed and synthesized based on 1, 8-naphthalimide. The probe displayed response to Ho3+ with a fluorescence decrease at 512nm and enhancement at 480nm, accompanying with a distinct fluorescence change from bright yellow-green to cyan. Besides, the probe exhibited a lower detection limit (6×10−8M) and could be used in intracellular fluorescence imaging. To the best of the knowledge, it was the first ratiometric fluorescent probe for Ho3+ detection. This probe was expected to be a useful tool for further elucidating the roles of Ho3+ in materials, biology and environment.
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