Abstract
AbstractThis study compared the capacity of high‐repetition giant‐set resistance training (HGRT) and high‐intensity interval training (HIIT) to decline C‐reactive protein (CRP), interleukin (IL)‐6, soluble IL‐6 receptor (SIL‐6R), IL‐18, and insulin resistance markers in long‐ (5–10 years) and short‐term (1–4 years) overweight men. Another purpose was to compare these markers between the two populations. Firstly, eligible participants were matched based on age, body mass index, and aerobic fitness and then divided into a long‐ (n = 37) or short‐term (n = 32) overweight population. After that, the participants in each category were randomly assigned to HGRT (2 giant sets of 4‐exercise × 2 circuits at 30%–50% of one‐repetition maximum with a novel periodization), HIIT (4‐set × 4‐min of running at 80%–90% of HRmax), and control (CON, non‐exercising) groups. The well‐balanced training programs were performed in three weekly sessions for 12 weeks. This study showed that individuals with a longer history of being overweight have elevated baseline concentrations of CRP, SIL‐6R, and IL‐18 (all, p ≤ 0.04, effect size [ES] ≥0.65). Both training programs led to a similar reduction in insulin and homeostasis model assessment of insulin resistance versus CON (all p ≤ 0.03, ES ≥ 0.49) regardless of the duration of being overweight, although SIL‐6R was significantly reduced after HIIT versus pretest (both, p ≤ 0.03, ES = 0.17). The two exercises caused a significant decline in IL‐18 in the long‐term population versus CON, while HIIT was the only program that decreased CRP (all, p ≤ 0.04, 0.21 ≤ ES ≤ 0.34). Thus, it seems that overweight history plays a crucial role in deteriorating some of the biomarkers, and the two exercises have greater potential to attenuate IL‐18. However, HIIT might have a greater anti‐inflammatory effect (as indicated by CRP and SIL‐6R) than HGRT.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.