Abstract

A Novel Nomogram Integrating the Peripheral Blood Lymphocyte Subsets (PBL) Predicting Survival for Patients with Esophageal Squamous Cell Carcinoma (ESCC) Who Underwent Concurrent Chemoradiotherapy

Highlights

  • Purpose/Objective(s): To evaluate the alternations and prognostic value of Peripheral Blood Lymphocyte Subsets (PBL) in esophageal squamous cell carcinoma (ESCC) patients who underwent concurrent chemoradiotherapy

  • Using the least absolute shrinkage and selection operator (LASSO) regression model, we extracted the PBL features associated with overall survival (OS) and built a classifier

  • Our results indicated the profile of PBL undergone profound changes in ESCC patients pre- and post-treatment

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Summary

Introduction

A Novel Nomogram Integrating the Peripheral Blood Lymphocyte Subsets (PBL) Predicting Survival for Patients with Esophageal Squamous Cell Carcinoma (ESCC) Who Underwent Concurrent Chemoradiotherapy Purpose/Objective(s): To evaluate the alternations and prognostic value of PBL in ESCC patients who underwent concurrent chemoradiotherapy. Materials/Methods: We recruited 353 ESCC patients who had undergone concurrent chemoradiotherapy in our center between 2010 and 2015.

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