Abstract
Chronic Resynchronization Therapy (CRT) is aimed at restoring synchronous contraction of the Left Ventricle. Currently approximately 60-70% of patients realize objective improvements, the remainder exposed without benefit. Non-responsiveness has been associated with both lack of dyssynchrony and transmural scar in the region of both the LV and RV pacing leads. Late Gadolinum Enhancement (LGE) following gadolinium administration is a golden standard for the localization and quantification of myocardial scar, albeit contraindicated in up to one-third of heart failure patients due to renal insufficiency.
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