A Novel Method to Understand Neural Oscillations During Full-Body Reaching: A Combined EEG and 3D Virtual Reality Study.

Abstract

Virtual reality (VR) can be used to create environments that are not possible in the real-world. Producing movements in VR holds enormous promise for rehabilitation and offers a platform from which to understand the neural control of movement. However, no study has examined the impact of a 3D fully immersive head-mounted display (HMD) VR system on the integrity of neural data. We assessed the quality of 64-channel EEG data with and without HMD VR during rest and during a full-body reaching task. We compared resting EEG while subjects completed three conditions: No HMD (EEG-only), HMD powered off (VR-off), and HMD powered on (VR-on). Within the same session, EEG were collected while subjects completed full-body reaching movements in two conditions (EEG-only, VR-on). During rest, no significant differences in data quality and power spectrum were observed between EEG-only, VR-off, and VR-on conditions. During reaching movements, the proportion of components attributed to the brain was greater in the EEG-only condition compared to the VR-on condition. Despite this difference, neural oscillations in source space were not significantly different between conditions, with both conditions associated with decreases in alpha and beta power in sensorimotor cortex during movements. Our findings demonstrate that the integrity of EEG data can be maintained while individuals execute full-body reaching movements within an immersive 3D VR environment. Clinical impact: Integrating VR and EEG is a viable approach to understanding the cortical processes of movement. Simultaneously recording movement and brain activity in combination with VR provides the foundation for neurobiologically informed rehabilitation therapies.