Abstract

A novel method for the preparation of κ-carrageenan/chitosan polyelectrolyte complex (PEC) membrane capsules containing theophylline as a model drug was developed. The theophylline release from the capsules followed zero-order kinetics, and the release rates were independent of pH of the dissolution medium, suggesting that κ-carrageenan/chitosan PEC capsules could be a useful vehicle for controlled-release drug delivery.

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