Abstract
BackgroundA design concept of low-cost, simple, fully mechanical model of a mechanically ventilated, passively breathing lung is developed. An example model is built to simulate a patient under mechanical ventilation with accurate volumes and compliances, while connected directly to a ventilator.MethodsThe lung is modelled with multiple units, represented by rubber bellows, with adjustable weights placed on bellows to simulate compartments of different superimposed pressure and compliance, as well as different levels of lung disease, such as Acute Respiratory Distress Syndrome (ARDS). The model was directly connected to a ventilator and the resulting pressure volume curves recorded.ResultsThe model effectively captures the fundamental lung dynamics for a variety of conditions, and showed the effects of different ventilator settings. It was particularly effective at showing the impact of Positive End Expiratory Pressure (PEEP) therapy on lung recruitment to improve oxygenation, a particulary difficult dynamic to capture.ConclusionApplication of PEEP therapy is difficult to teach and demonstrate clearly. Therefore, the model provide opportunity to train, teach, and aid further understanding of lung mechanics and the treatment of lung diseases in critical care, such as ARDS and asthma. Finally, the model's pure mechanical nature and accurate lung volumes mean that all results are both clearly visible and thus intuitively simple to grasp.
Highlights
A design concept of low-cost, simple, fully mechanical model of a mechanically ventilated, passively breathing lung is developed
Determining the content of this minimal set is the crux of the model design problem, and is difficult for purely mechanical model
This paper presents a design of completely mechanical model of the human lung to identify and verify the fundamental mechanics of any mechanically ventilated lungs and the effect of Positive End Expiratory Pressure (PEEP) on recruitment
Summary
A design concept of low-cost, simple, fully mechanical model of a mechanically ventilated, passively breathing lung is developed. Physiological modelling with mechanical and/or mathematical models has been a major focus for many bioengineering researchers. Such models are useful in understanding the physiological function or process, and can lead to development of new treatments or strategies. A model can be used to simulate and predict a body's reaction to certain treatment, drugs, or dosages without testing it on a patient. These models can simulate weeks' worth of treatment in a compressed (page number not for citation purposes). Determining the content of this minimal set is the crux of the model design problem, and is difficult for purely mechanical model
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