Abstract

AbstractBisulfite (HSO3−) is associated with many physiological processes in living systems. High concentration of HSO3− may lead to many diseases. Herein, a simple levulinate‐based colorimetric fluorescent probe for HSO3− detection was designed and synthesized. The probe showed high selectivity for HSO3− detection with color changes from light pink to deep pink. Under the optimal test conditions, there is a good linear relationship between fluorescence intensity and concentrations of HSO3− in the range of 0–50 μM with detection limit of 1.04 nM. In addition, the probe was successfully applied to monitor HSO3− in living cells and zebrafish, which proved that the probe can be used to detect HSO3− in living systems.

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