Abstract

This study presents a novel liver disease classification method by applying pattern recognition technique to automatically segmented liver from the images of computed tomographic (CT) scans. The methodology comprises of disease classification by the extraction of textural features from focal liver region bearing tumors. Two types of liver textures are investigated in this study for classification accuracy judgement. First, original liver texture is considered for feature extraction. Second, liver is used for feature extraction. The CT image dataset comprises 308 liver samples with 193 samples of malignant tumor and 115 samples of benign tumor. The entire liver tissue bearing tumor is segmented from the CT image automatically in the pre-processing stage using fuzzy transformation function and morphological processing. Four sets of textural feature matrices are applied to the liver for feature extraction. Gray level co-occurrence matrix (GLCM), standard deviation gray level co-occurrence matrix (SDGLCM), seven-moment matrix (7MM) and seven-moment gray level co-occurrence matrix (7MGLCM) are the combinational feature matrices applied to classify the liver as malignant or benign using support vector machines (SVMs). The best classification accuracy is achieved for original liver texture by 7MGLCM, which is 97% with AUC = 0.99 for training dataset and 97.8% with AUC = 1 for test dataset.

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